What Types of Drugs May Interact with Vitamin A

What Types of Drugs May Interact with Vitamin A

What Types of Drugs May Interact with Vitamin A?

• Alcohol can exacerbate liver damage caused by high doses of vitamin A. Drinking alcoholic beverages with beef liver slices as a side dish is prevalent in some Asian cultures, which can lead to vitamin A toxicity. Furthermore, cholesterol-lowering drugs that hinder lipid absorption may also diminish vitamin A absorption.

• Long-term consumption of high doses of vitamin A can decrease vitamin K absorption, leading to vitamin K deficiency. Vitamin A enhances the drug action of warfarin. People who take warfarin to treat and prevent blood clots together with high-dose vitamin A should consult with health-care professionals. Safety Issues

• Overdose. Long-term consumption of high doses of vitamin A may cause hypervitaminosis A. Symptoms include blurred vision, lack of appetite, dry skin, and muscle weakness. High doses of vitamin A can cause liver damage as well as osteoporosis.

• Pregnant women. During pregnancy, women should take no more than 25,000 IU of vitamin A supplement daily to avoid hypervitaminosis A, which can lead to birth defects in infants.

• Recommended daily dose. Vitamin A is lipid-soluble and, once absorbed, will be retained in the body for a long time. It is recommended that you take no more than 10,000 IU of vitamin A per day.

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