What Is the Association Between Vitamin D and Lupus Erythematosus

What Is the Association between Vitamin D and Lupus Erythematosus?

• Lupus erythematosus patients have lower blood levels of vitamin D compared to healthy individuals. Studies have shown that low blood levels of vitamin D significantly elevated the risk of lupus erythematosus. Lupus erythematosus patients with sufficient blood levels of vitamin D have fewer flares and better control over the disease's symptoms.

• Lupus erythematosus patients tend to avoid outdoor activities because of sensitivity to sun exposure. However, avoidance of sun exposure can exacerbate vitamin D deficiency as well as the symptoms of the disease.

• Vitamin D inhibits the immune system's ability to produce autoimmune antibodies, enhances innate immunity, and prevents adaptive immunity. Adaptive immunity disorder is the major cause of lupus erythematosus.

Meta-analysis

• Vitamin D. A meta-analysis of 11 research articles explored the relationship between vitamin D and lupus erythematosus. Analysis confirmed that low blood levels of vitamin D exacerbated the symptoms of lupus erythematosus, while high blood levels of vitamin D alleviated the symptoms of the disease.

Recommendation

• Prevention. For people at risk of lupus erythematosus, take daily 800 IU vitamin D3 (11).

• Treatment. For lupus erythematosus patients, take daily 2,000 IU vitamin D3 (11).

YOU MAY ALSO LIKE