What Is the Association Between Vitamin D and Inflammatory Bowel Disease

What Is the Association Between Vitamin D and Inflammatory Bowel Disease

What Is the Association between Vitamin D and Inflammatory Bowel Disease?

• Inflammatory bowel disease patients have lower blood levels of vitamin D compared to healthy individuals. People who live far from the equator have a greater risk of inflammatory bowel disease. Maintaining high blood levels of vitamin D alleviates the symptoms of inflammatory bowel disease.

• Supplementation with vitamin D was found to mitigate the symptoms of Crohn's disease. The suggested daily dose of vitamin D3 is 5,000 IU for 24 weeks.

• Vitamin D deficiency increases the incidence of colon cancer in patients with Crohn's disease.

Meta-analysis

• Vitamin D. A meta-analysis of 14 research articles studied the relationship between vitamin D and inflammatory bowel disease in 1,891 participants, including 938 inflammatory bowel disease patients and 953 healthy individuals. Analysis has shown that patients with inflammatory bowel disease had lower blood levels of vitamin D compared to healthy controls. Recommendation

• Prevention. For people at risk of inflammatory bowel disease, take daily 800 IU vitamin D3 (11).

• Treatment. For inflammatory bowel disease patients, including those with ulcerative colitis and Crohn's disease, take 5,000 IU vitamin D3 (11) for 6 months, and after that, take daily 2,000 IU vitamin D3 (11).


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