What Is the Association Between Vitamin D and Graves’ Disease

What Is the Association between Vitamin D and Graves' Disease?

• Graves' disease patients have lower blood levels of vitamin D compared to healthy individuals.

• Radioactive iodine therapy is a therapeutic modality for treating Graves' disease. This treatment is effective only if the patient's blood level of vitamin D is higher than 20 ng/ml. Studies have shown that supplementation with vitamin D can significantly improve the effectiveness of radioactive iodine therapy for treating Graves' disease.


• Vitamin D. A meta-analysis of 26 research articles investigated the association between vitamin D and Graves' disease in 1,748 Graves' disease patients and 1,448 healthy individuals. The result has shown that Graves' disease patients had lower blood levels of vitamin D compared to healthy controls. Recommendation

• Prevention. For people at risk of Graves' disease, take daily 800 IU vitamin D3 (11).

• Treatment. For Graves' disease patients, take daily 2,000 IU vitamin D3 (11).