What Is the Association Between Vitamin B12 and Multiple Sclerosis

What Is the Association between Vitamin B12 and Multiple Sclerosis?

• Vitamin B12 can lower the blood level of homocysteine. A high blood level of homocysteine damages DNA and causes the premature death of nerve cells.

• Multiple sclerosis patients have low blood levels of vitamin B12 compared to healthy individuals.

Vitamin B12.

A meta-analysis of six research articles explored the relationship between blood levels of vitamin B12 and homocysteine and multiple sclerosis in 639 multiple sclerosis patients and 430 healthy individuals. The analysis confirmed that multiple sclerosis patients had a low blood level of vitamin B12 and a high blood level of homocysteine compared to healthy controls. In addition, vitamin B12 deficiency was found to increase the risk of multiple sclerosis.


• Prevention. For people at risk of multiple sclerosis, take daily 100 mcg vitamin B12 (9) and 800 IU vitamin D3 (11).

• Treatment. For multiple sclerosis patients, take daily 400 mcg vitamin B12 (9) and 2,000 IU vitamin D3 (11).