What Is the Association Between Calcium and Colorectal Cancer

What Is the Association between Calcium and Colorectal Cancer?

• Sufficient dietary intake of calcium, such as from drinking milk, may prevent colorectal cancer. Calcium decreases bacterial-induced inflammation and tumorigenesis in the gastrointestinal tract, thus reducing the risk of colorectal cancer.

• Supplementation with calcium may reduce the risk as well as the recurrence of colorectal cancer.

A meta-analysis of eight research papers examined the relationship between calcium supplements and colorectal cancer in 11,005 people. Daily doses of calcium supplements ranged from 333 to 2,229 mg. Analysis revealed that supplementation with calcium decreased the risk of colorectal cancer by 23%.

A meta-analysis of four randomized controlled trials conducted with 2,984 colorectal cancer patients evaluated the relationship between calcium supplements and the recurrence of colorectal cancer. Daily doses of calcium supplements ranged from 1,200 to 2,000 mg for 36–60 months. Analysis confirmed that calcium supplementation significantly reduced the recurrence of colorectal cancer.

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