What Are the Symptoms of Magnesium Deficiency

What Are the Symptoms of Magnesium Deficiency?

• The major symptoms of magnesium deficiency are muscle spasms, atrial fibrillation, and seizure. Although magnesium deficiency is rare, magnesium insufficiency is rather common. In the US, 65% of people have an insufficient dietary intake of magnesium, and 81% of people aged 71 years and older are magnesium insufficient.

• Certain acute and chronic diseases can give rise to magnesium deficiency. These diseases include digestive disorders and kidney and endocrine malfunctions. Digestive disorders include malnutrition, severe vomiting, acute and chronic diarrhea, and acute pancreatitis. Antacid medications can also lead to magnesium deficiency. Diuretics, hypercalcemia, acute renal failure, alcoholism, and renal toxins, such as cisplatin and amphotericin B, contribute to renal malfunctions. Endocrine malfunctions include type 2 diabetes, phosphate deficiency, hypoparathyroidism, and hyperparathyroidism.

Magnesium is an essential element that exists in an ionic form in biological systems. The magnesium ion is the fourth most abundant cation in the body and the second most abundant cation inside the cell. The human body contains about 25 g of magnesium, of which 60% is stored in the bones and the rest in various organs and tissues. Genetic DNA material is negatively charged, so the binding of cationic magnesium ions stabilizes the structural stability of the anionic DNA. Magnesium ions are also required to support the involvement of 300 different enzymes in various important physiological functions in the body.

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