What Are the Symptoms of Kashin-Beck Disease

What Are the Symptoms of Kashin-Beck Disease

Kashin-Beck disease is a chronic disease of the cartilage. The disease affects several millions of people living in 15 provinces in China from the northeastern to southwestern regions. Kashin-Beck disease is caused by selenium deficiency in the soil. Children and teenagers aged 5–15 are most vulnerable to the affliction.

What Are the Symptoms of Kashin-Beck Disease?

• Retarded bone growth due to the death of chondrocytes, causing shorter stature in children and teenagers

• Swelling in the joints, such as the shoulder blades, elbows, ankles, knees, fingers, and toes

• Shortened and hardened bones

Meta-analysis

• Selenium. A meta-analysis of 15 research papers explored the association between selenium supplements and Kashin-Beck disease in 2,359 children in affected regions in China. Analysis has shown that supplementation with selenium reduced the incidence rate of Kashin-Beck disease by 84% in affected regions in China. 

Recommendation

• Prevention. For children in Kashin-Beck disease regions, take daily 50 mcg selenium (26).

• Treatment. For Kashin-Beck disease patients, take daily 100 mcg selenium (26).


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