What Are the Symptoms of Graves’ Disease

What Are the Symptoms of Graves' Disease?

• Anxiety and irritability

• Chest pain

• Hypertension

• Insomnia

• Fatigue

• Palpitations and an irregular heartbeat

• Heat intolerance, sweating easily, and clammy skin

• An enlarged thyroid gland or goiter

• Exophthalmoses (abnormal protrusion of the eyeball or eyeballs)

• Weight loss despite a good appetite

Graves' disease is an autoimmune disorder characterized by excessive production of thyroid hormones, causing hyperthyroidism. The pituitary gland in the brain produces thyroid-stimulating hormones that regulate thyroid function. Graves' disease patients produce an autoantibody that resembles the thyroid-stimulating hormone. The synergistic effect of the thyroid-stimulating hormone and autoantibody brings on the overproduction of thyroid hormones in the thyroid gland, leading to hyperthyroidism. In the US, 3 million people are afflicted with Graves' disease. The incidence rate is five times higher in women compared to men.

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