What Are the Risk Factors for Chronic Kidney Disease

What Are the Risk Factors for Chronic Kidney Disease

What Are the Risk Factors for Chronic Kidney Disease?

• Diabetes. High blood glucose causes damage to kidney cells, resulting in metabolic disorders and mitochondrial malfunction. Mitochondrial malfunction results in the loss of energy production and deterioration of renal functions, leading to chronic kidney disease. Diabetes-related chronic kidney disease is the major cause of kidney failure. • Hypertension. Hypertension causes damage to the arterial vessels and further aggravates the symptoms of chronic kidney disease.

• Smoking. Cigarette smoke contains harmful chemicals that enter the bloodstream and travel to the kidneys. These toxic chemicals cause oxidative damage to the kidneys and induce insulin resistance in renal cells, thus increasing the risk of chronic kidney disease.

• Obesity. Obesity fattens glomerular cells and reduces the glomerular filtration rate. A decrease in glomerular filtration rate is a sign of chronic kidney disease.

• High triglycerides. High blood levels of triglycerides are associated with atherosclerosis, which is a contributing factor to chronic kidney disease. In addition, a low glomerular filtration rate in chronic kidney disease further elevates blood levels of triglycerides.

• Age. Aging accelerates renal fibrosis, glomerulosclerosis, tubular atrophy, atherosclerosis, and renal dysfunction, thus increasing the risk of chronic kidney disease.

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