What Are the Complications Associated with Obesity

What Are the Complications Associated with Obesity?

• Type 2 diabetes. Obesity increases the incidence of insulin resistance and type 2 diabetes. Fat tissues in obese people release a large amount of fatty acids, glycerol, inflammatory cytokines, and other chemicals into the bloodstream, which can lead to insulin resistance. Chronic insulin resistance injures insulin-producing beta cells in the pancreas. Insulin resistance and the death of beta cells are both associated with type 2 diabetes.

• Myocardial infarction. Obese people tend to suffer from hypertension and hypercholesterolemia, heightening the risk of blood clot formation and myocardial infarction. • Hypertension. Obesity increases vasoconstrictor contents like renin, angiotensin, and aldosterone in the bloodstream, causing hypertension.

• Cancer. Obesity increases the incidence rate and mortality of colorectal cancer, pancreatic cancer, breast cancer, lymphatic cancer, and prostate cancer. It triggers the body to produce cancer risk factors, such as leptin, adiponectin, interleukin-6, and tumor necrosis factor-alpha. The abovementioned obesity-related cancers tend to develop near white adipose tissues in the digestive tract, pancreas, breast, lymphatic gland, and prostate gland. White adipose tissues cause cancerous cells to grow, proliferate, and migrate into neighboring cells.

• Stroke. Excessive abdominal fat increases the risk of ischemic stroke. Body mass index is often used in predicting the risk of stroke. However, recent studies have shown that abdominal fat is more accurate in predicting the risk of stroke compared to body mass index, particularly in young people. Obesity also raises cerebral blood pressure, reduces blood flow, and diminishes cerebral perfusion, all of which are risk factors for stroke.

• Fatty liver disease. Obesity is associated with fatty liver disease. In obese people, excessive fat is stored in the liver, leading to fatty liver disease.